吴建辉

　　 　　

一、基本信息

吴建辉，男, 1987年1月出生，吉林洮南人，农学博士，作物遗传育种专业，副教授，博士生导师，西北农林科技大学农学院植物科学系/旱区作物逆境生物学国家重点实验室。

二、学习工作经历

2011年6月毕业于西北农林科技大学农学院农学专业，获农学学士学位，2017年6月毕业于西北农林科技大学植物保护学院植物病理专业，获农学博士学位。同年7月受聘于旱区作物与逆境生物学学科群，从事科学研究工作。2019年1月进入西北农林科技大学生命科学学院生物学流动站开展博士后研究，2020年7月留校任教，同期被聘为副教授。

三、研究方向

面向作物智能育种理论和实践关键问题，以小麦基因资源数字化发掘和智能化创新为导向，以AI驱动的多组学大数据发掘为研究手段，重点研究：

（1）小麦全基因组抗病基因资源规模化鉴定、基因间互作网络解析及组装效应评价，构建小麦抗病育种关键基础数据库；

（2）建立并优化提取小麦高通量抗病表型特征的算法，探索小麦全基因组抗病结构性组装和系统性抗病表现关联性的基本规律，为打造小麦种业数据集、新种质和工具链创新平台奠定基础。

四、本科教学课程

承担本科生《作物数智育种》、《表型组学》、《植物表型组学》、《精准作物表型》以及《农业生物技术》等课程。

五、承担科研项目情况

1.国家自然科学基金面上项目：小麦多抗基因Yr29的图位克隆及育种应用研究（32472103），2025.01-2028.12，50万元，主持

2.国家自然科学基金面上项目：小麦持久抗条锈病位点QYr.nwafu-4BL (YrRC)的图位克隆与分子育种应用研究（32272088），2023.01-2026.12，55万元，主持

3.青海省重点研发与转化计划项目：小麦兼抗多种病害种质精准创制与高效应用（2025-NK-129），2025.01-2027.12，200万元，任务负责人，在研

4.国家重点研发计划项目：小麦条锈病灾变机制与可持续防控技术研究，课题小麦免疫调控与合理利用研究/中国小麦主栽品种抗病基因类型分析及鉴定（2021YFD1401003/2021YFD1401003-07），2021.07-2024.06，90万元，子课题负责人，结题

5.中国博士后科学基金特别资助，小麦成株期抗条锈病主效位点YrSnb.1 精细定位及候选基因TaSTPK 的功能鉴定（2022T150538），2022.01-2024.12，18万元，主持，结题

6.国家自然科学基金青年项目：小麦持久抗条锈病主效基因YrRC-4BL的精细定位及候选基因分析（31901494），2020.01-2022.12，25万元，主持，结题

7.国家自然科学基金创新研究群体：粮食作物重大真菌病害（32421004），2025.01-2029.12，1000万，参与，在研

8.陕西省农业科技创新驱动项目：优质多抗小麦新品种分子选育及其示范推广（NYKJ-2021-YL(XN)15），2021.06-2022.06，50万元，任务负责人，结题

9.青海省重点研发与转化计划项目：西北春麦区小麦抗病高产分子设计育种及示范应用（2022-NK-125），2022.01-2024.12，300万元，课题骨干，结题

10.博士后基金第65批面上项目：小麦持久抗条锈病基因Yr62的精细定位及应用（2019M653769），2019.06-2021.1，8万元，结题

六、其他学术成果

(一) 发表论文

发表中英文论文30余篇，其中近5年在Nature Genetics（2篇）、Cell Reports、Plant Cell & Environment、Plant Biotechnology Journal、Theoretical and Applied Genetics、The Crop Journal、中国农业科学、作物学报等农业科学TOP期刊发表 SCI收录论文18篇。（^＃第一作者；*通讯作者）

1.Wu Jianhui^#*, Ma Shengwei^#, Niu Jianqing^#, Sun Weihang^#, Dong Haitao^#, Zheng Shusong^#, Zhao Jiwen, Liu Shengjie, Yu Rui, Li Ying, Han Jinyu, Wang Yimin, Chen Tiantian, Zhang Chuanliang, Zhang Wenjing, Ding Bingyou, Chang Lu, Xue Wenbo, Zheng Weijun, Li Chunlian, Han Dejun^*, Kang Zhensheng^*, Zeng Qingdong^*, Ling Hongqing^* (2025) Genomics-driven discovery of superior alleles and genes for yellow rust resistance in wheat. Nature Genetics. 57(8): 2017-2027. 2025-07-22

2.Shen Kuocheng^#, Ye Botao^#, Yu Xuchang^#, Shen Peng^#, Yu Rui^#, Yin Changbin^#, Xu Xiaowan^#, Dong Jing^#, Wang Ziying, Wu He, Zang Yiming, Li Jiaxin, Peng Yanchun, Han Dejun, He Zhonghu, Zhang Xueyong, Li Junming, Hao Chenyang, Zhang Zhiliang, Kang Lipeng, Xu Song, Lu Fei^*, Hao Yuanfeng^*, Wu Tingting^*, Wu Jianhui^*, Guo Zifeng^*. Dissection of genomic drivers of spike morphology changes in wheat by high-throughput phenotyping. Cell Reports 2025, 44(8): 116120. 2025-08-26

3.Liu Lei^#, Han Jinyu^#, Zhang Dandan^#, Li Yuqing, Zhang Chuanliang, Liu Shengjie, Yan Ziyi, Zheng Weijun, Li Chunlian, Zeng Qingdong, Kang Zhensheng, Han Dejun, Zhang Wentao^*, Yao Qiang^*, Wu Jianhui^*. 2025. Genotyping by target sequencing (GBTS)-based genetic mapping uncovers synergistic interactions for stripe rust resistance in wheat cultivar Flanders. Theoretical and Applied Genetics, 138(8):187. 2025-07-21

4.Wang Xiaoting^#, Zhou Xinying^#, Han Jinyu^#, Yue Wenjie, Sun Weihang, Gao Tiantian, Liu Dan, Li Chenchen, Ma Xuehong, Jiang Pingtao, Ji Songhan, Yan Haohao, Zheng Weijun, Li Chunlian, Zeng Qingdong, Liu Shengjie, Zhang Xinmei, Kang Zhensheng, Han Dejun^*, Liu Zhiyong^*, Wu Jianhui^*. 2025. Identification and validation of stripe rust resistance on 7BL in wheat cultivar Aikang 58 through linkage and association analysis. Journal of Integrative Agriculture. https://doi.org/10.1016/j.jia.2025.04.030 2025-04-25

5.Zhao Jiwen^#, Dong Haitao^#, Han Jinyu^#, Ou Jingrui, Chen Tiantian, Wang Yuze, Liu Shengjie, Yu Rui, Zheng Weijun, Li Chunlian, Kang Zhensheng, Han Dejun, Zeng Qingdong^*, Wang Xiaojie^*, Ma Shengwei^*, Wu Jianhui^*. 2025. LWRR: Landscape of Wheat Rust Resistance towards practical breeding design. Stress Biology,5(1). 2025-04-14

6.Zhang Yibo^#, Huang Shuo^#,Li Yuqing^#, Cao Shuaiwei, Ren Hui, Xiang Mingjie, Dong Haitao, Han Jiangna, Zhao Ying, Zhang Xiangxue, Yuan Xunying, Wang Qilin, Wang Yajun, Ouyang Yi, Yang Zujun, Kang Zhensheng, Liu Shengjie, Wu Jianhui^*, Zeng Qingdong^*, Han Dejun^*. Rapid isolation of Yr9 via mutisoseq and qtl analysis of durable stripe rust resistance in wheat cultivar xingzi 9104. Stress Biology 2025, 5(1). 2025-04-30

7.Wang Meng^#*, Cheng Jie^#, Wu Jianhui^#, Chen Jiefei, Liu Dan, Wang Chenyang, Ma Shengwei, Guo Weiwei, Li Guangjie, Di Dongwei, Zhang Yumei, Han Dejun, Herbert J. Kronzucker, Xia Guangmin, Shi Weiming. 2024. Variation in TaSPL6-D confers salinity tolerance in bread wheat by activating TaHKT1;5-D while preserving yield-related traits. Nature Genetics, 56(6):1257-1269. 2024-05-27

8.Liu Yangyang^#, Yu Rui^#, Shen Liping^#, Sun Mengjing^#, Peng Yanchun, Zeng Qingdong, Shen Kuocheng, Yu Xuchang, Wu He, Ye Botao, Wang Ziying, Sun Zhiweng, Liu Danning, Sun Xiaohui, Zhang Zhiliang, Dong Jiayu, Dong Jing, Han Dejun, He Zhonghu, Hao Yuanfeng^*, Wu Jianhui^*, Guo Zifeng^*. 2024. Genomic insights into the modifications of spike morphology traits during wheat breeding. Plant, Cell & Environment, 47(12): 5470-5482. 2024-08-29

9.Yu Rui^#, Cao Xiaofeng^#, Liu Jia, Nie Ruiqi, Zhang Chuanliang, Yuan Meng, Huang Yanchuan, Liu Xinzhe, Zheng Weijun, Wang Changfa, Wu Tingting, Su Baofeng, Kang Zhensheng, Zeng Qingdong^*, Han Dejun^*, Wu Jianhui^*. 2024. Using UAV-based temporal spectral indices to dissect changes in the stay-green trait in wheat. Plant Phenomics,6. 2024-04-30

10.Wu Qimeng^#, Liu Lei^#, Zhang Dandan^#, Li Chenchen, Nie Ruiqi, Duan Jiangli, Wan Jufen, Zhao Jiwen, Cao Jianghao, Liu Dan, Liu Shengjie, Wang Qilin, Zheng Weijun, Yao Qiang, Kang Zhensheng, Zhang Wentao, Du Jiuyuan, Han Dejun, Wang Changfa^*, Wu Jianhui^*, Li Chunlian^*. 2024. Genetic dissection and identification of stripe rust resistance genes in the wheat cultivar Lanhangxuan 121, a cultivar selected from a space mutation population. Molecular Breeding,44(3):23. 2024-03-04

11.Liu Shengjie^#, Liu Dan^#, Zhang Chuanliang^#, Zhang Wenjing, Wang Xiaoting, Mi Zhiwen, Gao Xin, Ren Yong, Lan Caixia, Liu Xiukun, Zhao Zhendong, Liu Jianjun, Li Haosheng, Yuan Fengping, Su Baofeng, Kang Zhensheng, Li Chunlian, Han Dejun, Wang Changfa^*, Cao Xinyou^*, Wu Jianhui^*. 2023. Slow stripe rusting in Chinese wheat Jimai 44 conferred by Yr29 in combination with a major QTL on chromosome arm 6AL. Theoretical and Applied Genetics,136(8):175. 2023-07-27

12.Huang Shuo^#, Zhang Yibo^#, Ren Hui^#, Zhang Xin, Yu Rui, Liu Shengjie, Zeng Qingdong, Wang Qilin, Yuan Fengping, Singh Ravi P, Bhavani Sridhar, Wu Jianhui^*, Han Dejun^*, Kang Zhensheng^*. 2023. High density mapping of wheat stripe rust resistance gene QYrXN3517-1BL using QTL mapping, BSE-Seq and candidate gene analysis. Theoretical and Applied Genetics, 136(3):39. 2023-03-10

13.Tai Li^#, Wu Jianhui^#, Jing Yexing^#, Liu Huaizeng^#, Zeng Qingdong, Xu Xiaojing, Shi Shengdixin, Wang Hongjin, Liu Wenting, Sun Jiaqiang^*, Han Dejun^*, Chen Kunming^*. 2023. A genome-wide association study uncovers that TaPI4K-2A regulates pre-harvest sprouting in wheat. Plant Communications:100739. 2023-10-26

14.Huang Shuo^#, Zhang Yibo^#, Ren Hui^#, Li Xiang, Zhang Xin, Zhang Zeyuan, Zhang Chuanliang, Liu Shengjie, Wang Xiaoting, Zeng Qingdong, Wang Qilin, Singh RP, Bhavani S, Wu Jianhui^*, Han Dejun^*, Kang Zhensheng^*. 2022. Epistatic interaction effect between chromosome 1BL (Yr29) and a novel locus on 2AL facilitating resistance to stripe rust in Chinese wheat Changwu 357-9. Theoretical and Applied Genetics,135(7):2501-2513. 2022-06-20

15.Liu Shengjie^#, Wang Xiaoting^#, Zhang Yayun, Jin Yangang, Xia Zhonghua, Xiang Mingjie, Huang Shuo, Qiao Linyi, Zheng Weijun, Zeng Qingdong, Wang Qilin, Yu Rui, Singh Ravi P., Bhavani Sridhar, Kang Zhensheng, Han Dejun^*, Wang Changfa^*, Wu Jianhui^*. 2022. Enhanced stripe rust resistance obtained by combining Yr30 with a widely dispersed, consistent QTL on chromosome arm 4BL. Theoretical and Applied Genetics. 135(1):351-365. 2021-10-19

16.Zhou Cai'e^#, Liu Dan^#, Zhang Xu, Wu Qimeng, Liu Shengjie, Zeng Qingdong, Wang Qilin, Wang Changfa, Li Chunlian, Ravi P. Singh, Sridhar Bhavani, Kang Zhensheng, Han Dejun^*, Weijun Zheng^*, Wu Jianhui^*. 2022. Combined linkage and association mapping reveals two major QTL for stripe rust adult plant resistance in Shaanmai 155 and their haplotype variation in common wheat germplasm. Crop Journal. 10(3):783-792. 2021-11-01

17.Shengwei Ma, Meng Wang^*, Jianhui Wu, Weilong Guo, Yongming Chen, Guangwei Li, Yanpeng Wang, Weiming Shi, Guangmin Xia, Daolin Fu, Zhensheng Kang, Fei Ni^*. 2021. WheatOmics: a platform combining multiple omics data to accelerate functional genomics studies in wheat. Molecular Plant. 14: 1965-1968

18.Liu Shengjie^#, Huang Shuo^#, Zeng Qingdong^#, Wang Xiaoting, Yu Rui, Wang Qilin, Singh Ravi P., Bhavani Sridhar, Kang Zhensheng^*, Wu Jianhui^*, Han Dejun^*. 2021. Refined mapping of stripe rust resistance gene YrP10090 within a desirable haplotype for wheat improvement on chromosome 6A. Theoretical and Applied Genetics, 134: 2005-2021. 2021-03-08

19.Huang Shuo^#, Liu Shengjie^#, Zhang Yibo, Xie Yanzhou, Wang Xiaoting, Jiao Hanxuan, Wu Shushu, Zeng Qingdong, Wang Qilin, Singh Ravi P., Bhavani Sridhar, Kang Zhensheng, Wang Chengshe^*, Han Dejun^*, Wu Jianhui^*. 2021. Genome-wide wheat 55K SNP-based mapping of stripe rust resistance loci in wheat cultivar Shaannong 33 and their alleles frequencies in current Chinese wheat cultivars and breeding lines. Plant Disease, 105: 1048-1056. 2020-09-19

20.Jianhui Wu^#, Rui Yu^#, Haiying Wang^#, Cai’e Zhou, Shuo Huang, Hanxuan Jiao, Shizhou Yu, Xiaojun Nie, Qilin Wang, Shengjie Liu, Weining Song, Ravi. P Singh, Sridhar Bhavani, Zhensheng Kang^*, Dejun Han^*, Qingdong Zeng^*. 2021. A large-scale genomic association analysis identifies the candidate causal genes conferring stripe rust resistance under multiple field environments. Plant Biotechnology Journal. 19(1): 177-191. 2020-09-03

其他论文

1.Yu Shizhou^#, Wu Jianhui^#, Wang Meng^#, Shi Weiming, Xia Guangmin, Jia Jizeng, Kang Zhensheng*, Han Dejun*. 2020. Haplotype variations in QTL for salt tolerance in Chinese wheat accessions identified by marker-based and pedigree-based kinship analyses. Crop Journal. 8: 1011-1024.

2.Jianhui Wu^#, Xiaoting Wang^#, Nan Chen, Haiying Wang, Rui Yu, Shizhou Yu, Qilin Wang, Shuo Huang, Ravi P. Singh, Sridhar Bhavani, Zhensheng Kang, Dejun Han, Qingdong Zeng. 2020. Association analysis identifies new loci for resistance to Chinese Yr26-virulent races of the stripe rust pathogen in a diverse panel of wheat germplasm. Plant Disease. 104:1751-1762

3.Mu, Jingmei^#; Wu, Jianhui^#; Liu, Shengjie^#; Dai, Miaofei; Sun, Daojie; Huang, Shuo; Wang, Qilin; Zeng, Qingdong; Yu, Shizhou; Chen, Li; Kang, Zhensheng*; Han, Dejun*. 2019. Genome-wide linkage mapping reveals stripe rust resistance in common wheat (Triticum aestivum) Xinong1376. Plant Disease. 103:2742-2750.

4.Zeng Qingdong^#, Wu Jianhui^#, Liu Shengjie^#, Huang Shuo, Wang Qilin, Mu Jingmei, Yu Shizhou, Han Dejun*, Kang Zhensheng*. 2019. A major QTL co-localized on chromosome 6BL and its epistatic interaction for enhanced wheat stripe rust resistance. Theoretical and Applied Genetics. 132:1409-1424.

5.Qingdong Zeng^#, Jianhui Wu^#, Shuo Huang^#, Fengping Yuan, Shengjie Liu, Qilin Wang, Jingmei Mu, Shizhou Yu, Li Chen, Dejun Han*, Zhensheng Kang*. 2019. SNP-based linkage mapping for validation of adult plant stripe rust resistance QTL in common wheat cultivar Chakwal 86. Crop Journal. 7:176-186.

6.Huang Shuo^#, Wu Jianhui^#, Wang Xiaoting, Mu Jingmei, Xu Zhi, Zeng Qingdong, Liu Shengjie, Wang Qilin, Kang Zhensheng*, Han Dejun*. 2019. Utilization of the Genomewide Wheat 55K SNP Array for Genetic Analysis of Stripe Rust Resistance in Common Wheat Line P9936. Phytopathology. 109:819-827.

7.Qingdong Zeng^#, Jianhui Wu^#, Shengjie Liu, Xianming Chen, Fengping Yuan, Pingping Su, Qilin Wang, Shuo Huang, Jingmei Mu, Dejun Han*, Zhensheng Kang*. 2019. Genome-wide mapping for stripe rust resistance loci in common wheat cultivar Qinnong 142. Plant Disease. 103:439-447.

8.Jianhui Wu, Shuo Huang, Qingdong Zeng, Shengjie Liu, Qilin Wang, Jingmei Mu, Shizhou Yu, Dejun Han*, Zhensheng Kang*. 2018. Comparative genome-wide mapping versus extreme pool-genotyping and development of diagnostic SNP markers linked to QTL for adult plant resistance to stripe rust in common wheat. Theoretical and Applied Genetics. 131:1777–1792.

9.Jianhui Wu^#, Qingdong Zeng^#, Qilin Wang^#, Shengjie Liu, Shizhou Yu, Jingmei Mu, Shuo Huang, Hanan Sela, Assaf Distelfeld, Lili Huang, Dejun Han*, and Zhensheng Kang*. 2018. SNP-based pool genotyping and haplotype analysis accelerate fine mapping the genomic region associated with stripe rust resistance gene Yr26. Theoretical and Applied Genetics. 131: 1481-1496.

10.Jianhui Wu, Shengjie Liu, Qilin Wang, Qingdong Zeng, Jingmei Mu, Shuo Huang, Shizhou Yu, Dejun Han*, and Zhensheng Kang*. 2018. Rapid identification of an adult plant stripe rust resistance gene in hexaploid wheat by high-throughput SNP array genotyping of pooled extremes. Theoretical and Applied Genetics. 131:43-58.

11.Jianhui Wu^#, Qilin Wang^#, Liangsheng Xu, Xianming Chen, Bei Li, Jingmei Mu, Qingdong Zeng, Lili Huang, Dejun Han*, and Zhensheng Kang*. 2018. Combining SNP genotyping array with bulked segregant analysis to map a gene controlling adult-plant resistance to stripe rust in wheat line 03031-1-5 H62. Phytopathology. 108:103-113.

12.Jianhui Wu^#, Qilin Wang^#, Xianming Chen, Shengjie Liu, Haiyang Li, Qingdong Zeng, Jingmei Mu, Miaofei Dai, Dejun Han*, and Zhensheng Kang*. 2017. Development and validation of KASP-SNP markers for QTL underlying resistance to stripe rust in common wheat cultivar P10057. Plant Disease. 101: 2079-2087.

13.Jianhui Wu，Qilin Wang, Shengjie Liu, Shuo Huang, Jingmei Mu, Qingdong Zeng, Lili Huang, Dejun Han*, and Zhensheng Kang*. 2017. Saturation mapping of a major effect QTL for stripe rust resistance on wheat chromosome 2B in cultivar Napo 63 using SNP genotyping arrays. Frontiers in Plant Science. 8: 653.

14.Jianhui Wu,Qilin Wang, Xianming Chen, Meijie Wang, Jingmei Mu, Xingna Lv, Lili Huang, Dejun Han*, and Zhensheng Kang*. 2016. Stripe rust resistance in wheat breeding lines developed for central Shaanxi, an overwintering region for Puccinia striiformis f. sp. tritici in China. Canadian Journal of Plant Pathology. 38: 317-324.

15.刘丹^#, 周彩娥^#, 王晓婷, 吴启蒙, 张旭, 王琪琳, 曾庆东, 康振生, 韩德俊^*, 吴建辉^*. 2021. 利用集群分离分析结合高密度芯片快速定位小麦成株期抗条锈病基因YrC271. 作物学报. 48: 553-564.

16.张旭, 韩金妤, 李晨晨, 张丹丹, 吴启蒙, 刘胜杰, 焦韩轩, 黄硕, 李春莲, 王长发, 曾庆东, 康振生, 韩德俊, 吴建辉. 2023. 结合基因关联和转录组分析鉴定小麦成株期抗条锈病位点YrZ501-2BL的候选基因. 中国农业科学,56(8):1429-1443.

17.王轶民, 李莹, 董海涛, 张恒瑞, 常璐, 高田甜, 韩德俊, 吴建辉. 2025. SRO家族蛋白在小麦多倍化进程中的演化规律. 生物技术通报,41(5):70-81.

(二) 其他成果

1.专利

（1）小麦抗条锈病基因YrAK58功能性分子标记及其应用. 吴建辉;李晨晨;刘胜杰;韩金妤;张丹丹;王海英;韩德俊;曾庆东;王长发;李春莲;郑炜君;康振生, 2024-4-12, 中国, 专利号ZL 2023 1 0107394.X, 授权公告号CN 116024379 B

（2）一种与小麦抗条锈病基因Yr26紧密连锁的分子标记、引物及其应用. 曾庆东; 吴建辉; 刘胜杰; 王琪琳; 韩德俊; 康振生, 2022-1-30, 中国, 专利号ZL 2019 1 0214777.0, 授权公告号CN 109797240 B

（3）小麦抗条锈病基因QYr.nwafu-6BL.2的连锁KASP分子标记、引物及应用. 吴建辉; 曾庆东; 刘胜杰; 韩德俊; 康振生, 2022-2-23, 中国,专利号ZL 2019 1 0182783.2授权公告号CN 109735652 B

（4）烯丙胺类化合物用于制备防治小麦真菌病害药物的应用. 曾庆东，李翔，袁凤平，纪凡，刘佳劼，吴建辉，王琪琳，康振生，韩德俊. 2022- 05-20，中国，专利号ZL 2020 1 0897352.7 授权公告号CN 112106773 B

（5）一种16K小麦全基因组mSNP区段组合、基因芯片及应用. 曾庆东;刘胜杰;相明杰;吴建辉;王长发;郑炜君;李春莲;袁凤平;康振生;韩德俊. 2023-10-20，中国，专利号ZL 2022 1 0046225.5 授权公告号CN 114525353 B

（6）一种与小麦育种性状相关的SNP位点组合及其应用. 曾庆东;相明杰;刘胜杰;王长发;吴建辉;郑炜君;李春莲;袁凤平;康振生;韩德俊. 2023-05-16，中国，专利号ZL 2022 1 0833588.3 授权公告号CN 115181812 B

2. 品种审定

参与选育的小麦新品种西农863，于2022年通过国家品种审定（国审麦20220138）；省审品种西农287（陕审麦20241012号）、西农875（陕审麦20241004号）

3.指导学生获2021和2022届本科“百篇优秀毕业论文（设计）”，2022/2025年校级优秀学术型硕士学位论文等

七、联系方式

通讯地址：陕西杨凌区邰城路3号西北农林科技大学农学院

邮编：712100 

Email: wujh@nwafu.edu.cn

ORCID: https://orcid.org/0000-0001-8154-1199

ResearcherID: https://www.researchgate.net/profile/Jianhui_Wu6

（数据截止2025.9）