
一、基本信息
宋宝兴,男,1987年9月出生于山东德州。植物学专业博士,西北农林科技大学教授、博士生导师。入选国家高层次人才青年项目。《BMC Genomics》和《New Crops》杂志编委,《Beverage Plant Research》《iMeta》《Journal of Integrative Agriculture》期刊青年编委。担任《Nature Plants》《Genome Research》《Bioinformatics》等杂志审稿人。
二、学习工作经历
2023-至今西北农林科技大学教授,博士生导师
2018-2022 美国康奈尔大学博士后
2014-2018 德国马克斯·普朗克植物育种研究所博士
2010-2013 西北农林科技大学硕士
2006-2010 郑州大学学士
三、研究方向
致力于通过禾本科作物(玉米、小麦等)和野生近缘种的遗传研究,实现高效、环境友好、可持续的农业发展模式。通过开发并应用前沿的分子进化和群体遗传学理论,挖掘长期进化过程中的关键农艺性状和环境适应性的主效基因,解析其分子机制,并应用于分子设计育种。
课题组致力于培养善于独立思考、勇于探索、具有领导力的青年科学家。欢迎生命科学、数学或计算机科学相关背景的学生报考。鼓励有意向攻读硕士或博士学位的同学提前以实习生或科研助理的身份加入实验室进行深入了解,课题组将优先考虑在本实验室有过实习经历的申请人。
四、科研成果
1、代表性论文(#,equal contribution;*,corresponding)
1)Jianxin Bian#, Guang Yang#, Dong Xu#, Yan Zhang#, Yanzhe Jia#, Guifen Zhang, Zhen Qin, Shuangxing Zhang, Yiqiao Wang, Mengmeng Jiang, Yan Pan, Bin Chen, Fangyu Liu, Yuqing Lu, Shuai Ding, Jiabo Wang, Can Yuan, Yongming Chen, Shoucheng Liu, Hang He, Shuai Wang, Qidi Zhu, Shisheng Chen*, Qing Sang*, Xing Wang Deng*, Hude Mao*, Xiaojun Nie*, Baoxing Song*. A pangenome of tetraploid wheat reveals the genetic architecture underlying domestication and genomic diversity for breeding. Nature Genetics. 2026
>> Xiaojun Nie, Baoxing Song. A tetraploid wheat pangenome reveals genomic variation and domestication footprints. Nature Genetics. 2026
2)Shuai Wang, Merritt Khaipho-Burch, Lynn C. Johnson, Zachary R. Miller, Peter Bradbury, Doug Speed, William J. Allen, M. Cinta Romay, Jiquan Xue, Edward S. Buckler, Guillaume P. Ramstein*, Baoxing Song*. Predicted protein 3D structures provide essential insights into the genetic architecture underlying phenotypic diversity in maize. Genome Research. 2026
3)Xiaodong Li#, Yan Zhang, Rui Zhang, Zhiyu Liu, Jiquan Xue, Baoxing Song*. quota_Anchor: a strand and whole genome duplication–aware collinear gene identification tool. aBIOTECH. 2026
4)Huawei Feng#, Wenjuan Fan, Min Liu, Jiaqian Huang, Bosheng Li, Qing Sang* and Baoxing Song*. Cross-species single-nucleus analysis reveals the potential role of whole-genome duplication in the evolution of maize flower development. BMC Genomics. 2025
5)Jinwei Yang#, Hongna Li#, Mengyu Li#, Rui Song#, Tao Shen, Guiping Wang, Dong Xu, Ming Hao, Aolin Jia, Shams ur Rehman, Lei Hua, Yanyan Liang, Cheng Chi, Caixia Lan, Xing Wang Deng, Jorge Dubcovsky, Baoxing Song*, Xiaodong Wang*, Shisheng Chen*. Genome-assisted identification of wheat leaf rust resistance gene Lr.ace-4A/Lr30. Nature Communications. 2025
6)Weiwei Fang, Haiying Yang, Huawei Feng, Baoxing Song*, Qing Sang*. Genome level identification of transcription start sites by nanoCAGE sequence in soybean. Scientific Data. 2025
7)Huafeng Zhou, Xiaoquan Su* and Baoxing Song*. ACMGA: a reference-free multiple-genome alignment pipeline for plant species. BMC Genomics. 2024
8)Guang Yang#, Yan Pan#, Wenqiu Pan#, Qingting Song, Ruoyu Zhang, Wei Tong, Licao Cui, Wanquan Ji, Weining Song, Baoxing Song*, Pingchuan Deng*, Xiaojun Nie*. Combined GWAS and eGWAS reveals the genetic basis underlying drought tolerance in emmer wheat (Triticum turgidum L.). New Phytologist. 2024
9)Baoxing Song*, Edward S. Buckler, Michelle C. Stitzer*. New whole-genome alignment tools are needed for tapping into plant diversity. Trends in Plant Science. 2023
10)Baoxing Song*, Santiago Marco-Sola, Miquel Moreto, Lynn Johnson, Edward S. Buckler*, Michelle C. Stitzer*. AnchorWave: Sensitive alignment of genomes with high sequence diversity, extensive structural polymorphism, and whole-genome duplication. PNAS. 2022
11)Baoxing Song*, Edward S. Buckler, Hai Wang, Yaoyao Wu, Evan Rees, Elizabeth A. Kellogg, Daniel J. Gates, Merritt Khaipho-Burch, Peter J. Bradbury, Jeffrey Ross-Ibarra, Matthew B. Hufford and M. Cinta Romay*. Conserved noncoding sequences provide insights into regulatory sequence and loss of gene expression in maize. Genome Research. 2021
12)Baoxing Song, Richard Mott, Xiangchao Gan*. Recovery of novel association loci in Arabidopsis thaliana and Drosophila melanogaster through leveraging INDELs association and integrated burden test. PLoS Genetics. 2018
13)Baoxing Song*#, Qing Sang#, Hai Wang, Huimin Pei, XiangChao Gan* and Fen Wang*. Complement Genome Annotation Lift Over Using a Weighted Sequence Alignment Strategy. Frontiers in Genetics. 2019
14)Fen Wang*#, Baohui Zhang#, Di Wen#, Rong Liu, Xinzhuan Yao, Zhi Chen, Ren Mu, Huimin Pei, Min Liu, Baoxing Song* and Litang Lu*. Chromosome-scale genome assembly of Camellia sinensis combined with multi-omics provides insights into its responses to infestation with green leafhoppers. Frontiers in Plant Science. 2022
15)Fen Wang, Zhi Chen, Huimin Pei, Zhiyou Guo, Di Wen, Rong Liu, Baoxing Song*. Transcriptome profiling analysis of tea plant (Camellia sinensis) using Oxford Nanopore long-read RNA-Seq technology. Gene. 2021
16)Fen Wang#, Baoxing Song#, Xing Zhao, Yaotian Miao, Dengyun Li, Na Zhou, Pengfei Jiang, Qing Sang, Jingfei Huang, Deli Zhang*. Prediction and analysis of the protein-protein interaction networks for chickens, cattle, dogs, horses and rabbits. Current Bioinformatics. 2016
17)Baoxing Song#, Fen Wang#, Yang Guo, Qing Sang, Min Liu, Dengyun Li, Wei Fang, Deli Zhang. Protein–protein interaction network‐based detection of functionally similar proteins within species. Proteins: Structure, Function, and Bioinformatics. 2012
18)Baoxing Song, Xiaoquan Su, Jian Xu, Kang Ning*. MetaSee: an interactive and extendable visualization toolbox for metagenomic sample analysis and comparison. PLoS One. 2012
2、软件著作权
(1) 宋宝兴; GEnomic sequence and genome structure ANnotation liftover, 2020SR0584132
(2) 宋宝兴; AnchorWave软件1.2.2, 2024SR0297907
3、大会报告
(1)AnchorWave: sensitive alignment of genomes with high diversity, structural polymorphism and whole-genome duplication variation. 2022 Maize Genetics Meeting, 美国圣路易斯
(2)AnchorWave: sensitive alignment of genomes with high diversity, structural polymorphism and whole-genome duplication. Biodiversity Genomics 2022, 美国加州戴维斯
(3)The Development of Whole-Genome Alignment Tools for Plant Species. PAG Asia 2024
(4)宋宝兴,解析祖先种质遗传多样性,解锁小麦育种密码。小麦族基因组学与分子育种论坛 2026
五、联系方式
通讯地址:陕西杨凌邰城路3号西北农林科技大学农学院
邮编: 712100
E-mail: bs674@nwafu.edu.cn