一、基本信息
卢海彬，男，1981年04月生，河南新乡人，西北农林科技大学副教授。2003年获得河南农业大学生物技术专业学士学位；2010年获得北京大学理学博士学位。
二、学习工作经历
学习经历：
2004-2010 北京大学和北京生命科学研究所
1999-2003 河南农业大学
工作经历：
2016-至今 副教授 西北农林科技大学
2015/01-02 访问学者 西班牙国家生物技术中心
2013-2015 博士后 西班牙农业基因组研究中心
2011-2013 博士后 德国马普植物育种研究所
2010-2011 研究助理 中国农业科学院植物保护研
三、研究方向
利用分子生物学、细胞生物学、遗传学和生物信息学等技术研究植物根部与病原菌相互作用的分子机制、马铃薯青枯病的抗性机制、植物免疫与植物生长的交叉信号。
1.植物根部与病原菌相互作用的分子机制：青枯病菌和丁香假单胞菌都可以造成植物根部结构的变化（如下图，抑制主根生长、侧根形成、根尖细胞死亡等）。这种表型的变化促进病原菌进入植物体内。我们以此为模型研究植物根部与病原菌的相互作用包括：病原菌如何改变根部结构，植物如何来防止根部结构的变化。
2.马铃薯青枯病抗性机制：青枯病菌通过根部侵入马铃薯，造成植株的枯萎死亡，导致马铃薯绝收（如下图中Desiree发病， O和P不发病）。此外，青枯病菌还可以侵染如番茄、烟草和苜蓿等其他重要经济作物和园艺植物。研究植物青枯病抗病分子机制对培育作物新品种，对保护生态环境和国家粮食安全具有重要意义。
3.植物抗病性与植物生长之间拮抗作用的分子机制：植物抗病性的增加会抑制植物的生长发育，进而降低作物的产量。研究它们之间的“交叉对话”可以促使培育高产、高抗病性的作物新品种。
四、本科教学课程
本科生教学课程包括《作物基因工程》和《设计生命：基因组编辑技术的过去、现在和未来》等。
五、承担科研项目情况
主持国家自然科学基金、陕西省科技计划、宁夏农林科学院对合作项目和宁夏重点研发计划等项目
六、学术成果
Xiang Wang, Qichang Gong, Shengyang Cheng, Ning Qin, Tao Cao, Yue Chen, Dongdong Wang, Marc Valls, Nuria S. Coll, Qin Chen, Cuizhu Zhao, and Haibin Lu*. Cytokinin plays a multifaceted role in Ralstonia solanacearum-triggered plant disease development. 2024. Molecular Plant Pathology. e70045.
Yang Niu, Shouyang Fu, Gong Chen, Huijuan Wang, Yisa Wang, JinXue Hu Xin Jin, Mancang Zhang, Mingxia Lu, Yizhe He, Dongdong Wang, Yue Chen, Yong Zhang，Núria. Coll6, Marc Valls, Cuizhu Zhao*, Qin Chen* and Haibin Lu*. Different epitopes of Ralstonia solanacearum effector RipAW are respectively recognized by two Nicotiana species and trigger immune responses. 2021. Molecular Plant Pathology. doi.org/10.1111/mpp.13153.
Li, W., Chen, Y., Ye, MH., Lu, H., Wang, DD and Chen, Q. 2020. Evolutionary History of the C-repeat binding factor/dehydration-responsive element-binding 1 (CBF/DREEB1) protein family in 43 plant species and characterization of CBF/DREB1 proteins in Solanum tuberosum. BMC Evolutionary Biology. 20: 142
Qin, N., Zhang, RZ., Zhang, MC., Niu, Y., Fu, SY., Wang, YS., Wang, DD., Chen, Y., Zhao, CZ., Chen, Q and Lu, H. 2020. Global profiling in Arabidopsis root upon Ralstonia solanacearum infection. Genes. 11. 1078
Wang, H., Hu, J., Lu, Y., Zhang, M., Qin, N., Zhang, R., He, Y., Wang, D., Chen, Y., Zhao, C., Coll, S., Valls, M., Chen, Q and Lu, H. 2019. A quick and efficient hydroponic potato infection method for evaluating potato resistance and Ralstonia solanacearum virulence. Plant Methods. 15：145. DOI. 10.1186/s13007-019-0530-9. (Corresponding author)
Zhao, C., Wang, H., Lu, Y., Hu, J., Qu, L., Li, Z., Wang, D., He, Y., Valls, M., Coll, NS., Chen Q and Lu, H. 2019.Deep sequencing reveals early reprogramming of arabidopsis root transcriptomes upon Ralstonia solanacearum infection. MPMI.32: 813-827. (Corresponding author)
Lu, H., Lema, S., Planas-Marques, M., Alonso-Diaz, A., Valls, M. and Coll N. 2018 Type three secretion-dependent and –independent phenotypes caused by Ralstonia solanacearum in Arabidopsis root. MPMI. 31:175-184.
Zuluaga, A. P*., Sole, M*., Lu, H*., Gongora-Castillo, E., Coll, N. S., Buell, C. R. and Valls, M. 2015. Transcriptome response to Ralstonia solanacearum infection in the roots of the wild potato Solanum commersonii. BMC Genomics. 16:246 (* These authors contributed equally to this work).
Lu, H., Chandrasekar, B., Oeljeklaus, J., Misas-Villamil, J., Wang, Z., Shindo, T., Bogyo, M., Kaiser, M. and Van der Hoorn, RAL. 2015. Subfamily-specific fluorescent probes for Cys proteases display dynamic protease activities during seed germination. Plant Physiology.168:1462-1475.
Lu, H., Wang, Z., Shabab, M., Verhelst, S. H., Kaschani, F., Kaiser M., Bogyo, M. and Van der Hoorn, R.A.L. 2013. A substrate-inspired probe monitors translocation, activation, and subcellular targeting of bacterial type Ⅲ effector protease AvrPphB. Chemistry & Biology. 20:168-176 (Highlighted)
Li, W., Ahn, I., Ning, Y., Park, C., Zeng, L., Whitehill, J., Lu, H., Zhao, Q., Ding, B., Xie Q., Zhou J., Dai, L. and Wang, G.. 2012. The U-Box/ARM E3 ligase PUB13 regulates cell death, defense, and flowering time in Arabidopsis. Plant Physiology. 159:239-250.
Zhang, J*., Lu, H*., Li, X., Li, Y., Cui, H., Wen, C., Tang, X., Su Z. And Zhou, J. 2010. Effector-triggered and Pathogen-associated molecular pattern-triggered immunity differentially contribute to basal resistance to Pseudomonas syringae. Molecular Plant-Microbe Interactions. 23:940-948.
Lu, H”, Feng, N., and Zou, Y. 2010. Overexpression AHL20 negatively regulates defense in Arabidopsis. Journal of Integrative Plant Biology. 52:801-808
Peng, Z., Zhou, X., Li, L., Yu, X., Li, H., Jiang, Z., Cao, G., Bai, M., Wang, X., Jiang, C., Lu,H., Hou, X., Qu, L., Wang, Z., Zuo, J., Fu, X., Su, Z., Li, S. and Guo, H. 2009. Arabidopsis hormone database: a comprehensive genetic and phenotypic information database for plant hormone research in Arabidopsis. Nucleic Acids Research. 37: D975-D982.
七、联系方式
通讯地址：陕西杨凌邰城路3号
邮编：712100
E-mail：luhaibin011@163.com
